Urban legend.
there are 3 variables, the camshaft, the lifters, and the lifter bores in the block (this affects how the lifter sits on its lobe). Change any of the 3, and a break-in will be required. Breaking-in a cam doesn't harden anything, the cams are hardened during manufacturing. What does hopefully happen during break-in is a good layer of ZDDP is left on the lobes.
By the way, the lifter "foot" & camshaft lobe are splash lubricated, which is why we run the motors at elevated rpm to break them in, more oil is splashing about.
My advice for anyone building a motor is to switch to a hydraulic roller cam if at all possible.
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