Sorry to take so long to reply. I have been away on vacation for 3 weeks. The major issues we had with the MSD self tuning units were surging at cruise and loss of power. The FAST unit we used was one of the first available and it was pulling fuel when the nitrous was engaged, never a good thing. We upgraded the unit to the Sportsman which allows custom tuning and it gained power even without the nitrous and it has worked flawlessly ever since. The owner says he would not hesitate to recommend that unit to anyone. There is a good chance the bugs may have been worked out of the systems. There have been several firmware updates since then for the FAST units so they may be better now. I would still to this day not recommend the MSD units simply because I was not impressed with much of anything with them and MSD doesnt have a good track record for me with any of their products. I have not used the Holley self tuning systems so I cannot give any input however if they are anything like the learning feature on the HP and Dominator systems it will likely work well. Temperatures should not be an issue at all.
Holley Dominator series would work well for you. The tricky part is finding a harness layout that works for your setup. You might be able to find a pre-built harness say for an LS engine which would have the terminations for the injectors and individual coils. You could also piece together a system using a universal main harness and individual sub harnesses to fit. This will all be based on trigger locations and throttle body and sensor locations.