I put the radiant tubing approx 8-12" apart with 2" styro insulation below the entire ground floor. Then staple up to the side of the joist on the 1st and 2nd floors. I used an instantaneous domestic water heater and zoned it like a heating system.
The key to estimating the tubing is simple .. 1' of tubing for every square foot if your doing 12" on center.
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