Since no one has answered I'll take a shot.
Most of your work will have to be done thru the hole in the firewall. You will have to wedge yourself in the car maybe even remove the seats if they are in the way. The actual removal and replacement is fairly easy and just like any other ford V8.
Please keep in mind I have not had to replace one in my pantera yet but have done many on my mustangs.
Burping air out of the pantera cooling system will be a challenge. I understand there is a great tool for this someone posted about a few weeks back.