Read sticky #3 and #4, it will answer many questions for you.
Im no expert, but I've read enough about Webers to know you need a special cam to run webers, so I'd inquire about that for sure.
I've read that 2 bolt blocks are fine, unless you're going for super high RPM's. I believe almost all the cleveland blocks are 2 bolt.
There are others here that can help you with what head/piston combos to run as well.
I've learned so much from this forum, the knowledge within the people on this forum is incredible.
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