BD,
Your meaning of artistry in the engine bay is not real clear to me. But I'll do my best to give a quick answer.
Your power goal of 400 bhp could be easily achieved with head porting, a good exhaust system, ignition upgrade, possibly a better intake & carb, and a hydraulic roller cam. Turbos, blowers, etc are not needed.
David, on the other hand, aaaaaaahhhhhh! lol....
You've got 522 bhp, and yet you want more!
The turbos, even a pair of turbos, are less expensive than a single blower. That is the direct answer to bull dog's question.
But you must evaluate the whole project. There is very little room above the engine, no room left of the engine, and what room there is on the right hand side is mostly occupied by the alternator, the a/c compressor, the swirl tank & the overflow tank. There is little room on the front of the engine for an additional blower drive belt. The car was not designed to accomodate a blower or turbo.
Fred Terry designed a gorgeous blower system for his Pantera, actually incorporating 2 blowers. It fits under the engine screen and doesn't rob room from the luggage tub. But Mr Terry hand fabricated & engineered that system from scratch, roll your own, if you will. It entailed a conversion to fuel injection as well.
B&M once offered a kit to fit their blower onto the 351C, but it has gone out of production long ago. That kit was aimed at Mustangs & Torinos, not the Pantera. I have seen one picture of one such B&M blower installed on a Pantera, somehow the owner was able to make room for the blower drive belt. Perhaps by eliminating the a/c compressor.
Kirk Evans once designed a turbo system for the Pantera with the turbo perched above the motor & the carb on top of that. It was a tall system.
There are no kits available today, to install a blower or a turbo, you will be "rolling your own". What the vendors have settled upon as the best way to up the power of a Pantera, is the 7 liter Windsor crate motor.
Most often, owners installing blowers or turbos mount them behind the motor, which spoils the use of the luggage tub. The blowers will be driven off the flywheel or by a "jack shaft" that runs along side the motor.
Then there's the problem of where to install an intercooler that will allow a good stream of cool air to blow through it. Most often the intercooler ends up mounted where the a/c condensor was originally located. Let's not overlook the Pantera's cooling system, which also has limitations due to the small dimensions of the radiator.
Finally, it is usually advised to limit boost to about 7 psi unless the engine is modified to work with higher levels of boost. David, you have already experienced with your Mustang that 7 pounds of boost just wasn't the extra kick you were expecting.
If I personally decided I "must" have a blower in my Pantera, I would toss the Cleveland engine, buy a 8.2 deck Dart Windsor block with 4.125 bores, a fordged steel 3.25" stroker crank, and build a fuel injected 5.0 style motor with a KenneBell auto-rotor style blower. The smaller block would give me the additional room needed for the blower sitting on top of the motor.
If I decided I "must" have a turbo, I would copy the system designed by AK Miller back in the '70s, picture below.
Your friend on the DTBB, George